Enzymes and Inhibitors
QA Bio Inc QA-Bio, Inc. • Neuraminidase Au • recombinant from A. ureafaciens • 60 µls
Neuraminidase Au - 60 µls • Alpha (2-3,6,8,9) Neuraminidase (Sialidase) cleaves all non-reducing terminal neuraminic acid residues from complex carbohydrates and glycoproteins.
ABclonal Technology c-Abl Rabbit mAb
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes including cell division adhesion differentiation and response to stress The activity of the protein is negatively regulated by its SH3 domain whereby deletion of the region encoding this domain results in an oncogene The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation suggesting a cell cycle function This gene has been found fused to a variety of translocation partner genes in various leukemias most notably the t(9 22) translocation that results in a fusion with the 5 end of the breakpoint cluster region gene (BCR MIM 151410) Alternative splicing of this gene results in two transcript variants which contain alternative first exons that are spliced to the remaining common exons
Enzo Life Sciences (S)-Mephenytoin, (5mg), CAS Number: 70989-04-7
Cytochrome P450 substrate. Substrate for determination of cytochrome P-450 polymorphism. Anticonvulsant. Formula: C12H14N2O2. MW: 218.3. CAS Number: 70989-04-7. Purity: ≥98% (TLC). Appearance: White solid. Solubility: Soluble in DMSO or ethanol. Long Term Storage: Ambient
Discovery Life Sciences HUMAN UGT1A4 0.5ML@5MG/ML
HumanmicrogramT1A4 SUPERSOMES 0.5mL This activity is catalyzed bymicrogramT1A4 which is expressed from humanmicrogramT1A4 cDNA using a baculovirus expression system
Diapharma Group, Inc. Chromogenix S-2765, 25 mg
Chromogenix S-2765 is a chromogenic substrate for determination of Factor Xa activity. It is also very sensitive to trypsin. S-2765 is suitable for measuring FXa inhibition in heparin anti-Xa assays and antithrombin anti-Xa assays.
Apexbio Technology LLC D-Luciferin (potassium salt) 115144-35-9 1g
D-Luciferin (potassium salt) a potassium salt derivative of D-luciferin serves as the bioluminescent substrate for firefly luciferase The enzyme-mediated oxidation of D-luciferin in the presence of ATP and oxygen produces bioluminescent emission at approximately 560 nm without the need for external excitation This property is applied extensively in bioluminescence imaging (BLI) experiments including live-cell and small-animal imaging Cells genetically engineered to express luciferase utilize D-luciferin to generate optical signals facilitating non-invasive visualization and tracking of biological events such as tumor growth gene expression dynamics in vivo distribution and therapeutic responses
Cayman Chemical N-Oleoyl ProlIn 5mg
An endogenous N-acyl amine that is decreased in lumbar spinal cord after capsaicin administration (1 UG/10 µl) and has surfactant properties (critical micelle concentration = 4.8 µM)
Cayman Chemical N-Oleoyl ValIn 10mg
An endogenous N-acyl amine; antagonist at TRPV3; increases after acute lung injury in mouse lung tissue
Gold Biotechnology Inc Lysozyme, Egg White 5 g
Lysozyme is an enzyme capable of breaking down the bacterial cell wall, and is typically used to enhance protein extractions or nucleic acid extractions. It works by hydrolyzing the 1,4-β-linkages located between the N-acetylmuramic acid and the N-acetyl-D-glucosamine residues in peptidoglycan.
Gold Biotechnology Inc D-Luciferin, Potassium Salt (Proven and Published™) 1 g
Luciferin is a common bioluminescent reporter used for in vivo imaging of the expression of luciferase. This water soluble substrate for the firefly luciferase enzyme utilizes ATP and Mg2+ as cofactors to emit a characteristic yellow-green emission in the presence of oxygen, which shifts to red light in vivo at 37°C. Through the utilization of ATP, the reaction can be further used to indicate the presence of energy or life in order to function as a life-death stain.
ABclonal Technology Endonuclease VIII
Endonuclease VIII originates from E.coli and possesses both N-glycosylase and AP-endonuclease activity. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site). The AP-endonuclease the phosphodiester bond at the AP site, forming 3’-P and 5’-P ends. Damaged bases recognized and removed by Endonuclease VIII include: urea, 5, 6-dihydroxythymine, thymine glycol, 5-hydroxy-5-methylhyd antoin, uracil glycol, 6-hydroxy-5, 6-dihydrothymine and methylhydroxy- methyluracil.
ABclonal Technology Mth RNA Ligase
Mth RNA Ligase is an ATP-dependent ligase that can efficiently convert 5-phosphorylated single-stranded DNA into 5-adenylated DNA. The kit has been optimized to yield high quantities of adenylylated DNA regardless of whether the 3 end of the single-stranded DNA has been aminated or otherwise modified. Typically, the modification efficiency can reach over 95%.
Biotium Coelenterazine HCP
Coelenterazine hcp is a synthetic derivative of coelenterazine. Its aequorin complex generates luminescence intensity 190 times higher and has a faster response time to calcium compared to native coelenterazine.Coelenterazines are luminescent enzyme substrates for apoaequorin and Renilla luciferase. Apoaequorin is used as a calcium indicator. It binds coelenterazine to form an aequorin complex that emits light upon calcium binding and measures concentrations ~0.1 uM to >100 uM. Renilla luciferase is widely used as a reporter of transcription regulation and as a donor in bioluminescence resonance energy transfer (BRET) to study protein-protein interactions. Coelenterazines are also used for chemiluminescent detection of superoxide anions and peroxynitrite in cells or tissues. Coelentrazine analogs and water-soluble Aquaphile™ Coelenterazines are also available.Properties : Yellow solid soluble in MeOH or EtOH; Store at -20°C, protect from light; C25H25N3O2; MW: 399.49.
STEMCELL Technologies Hyaluronidase, Size: 300000 U
Hyaluronidase is a polysaccharidase consisting of a single polypeptide chain of 450 amino acid residues and contains four disulfide bonds. Hyaluronidase is glycosylated and contains 5% mannose and 2.17% glucosamine (Borders & Raftery). Hyaluronidase cleaves endo-N-acetlyhexosaminic bonds in hyaluronic acid and chondroitin sulfate A and C to tetrasaccharide residues, as hyaluronic acid and chondroitin sulfate are often found in connective tissues. Hyaluronidase is frequently used with other proteases such as collagenase.